Eradication of B-ALL using chimeric antigen receptor–expressing T cells targeting the TSLPR oncoprotein

Adoptive transfer of T cells genetically modified to express chimeric antigen receptors (CARs) targeting the CD19 B cell–associated protein have demonstrated potent activity against relapsed/refractory B-lineage acute lymphoblastic leukemia (B-ALL). Not all patients respond, and CD19-negative relaps...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood
Egile Nagusiak: Qin, Haiying, Cho, Monica, Haso, Waleed, Zhang, Ling, Tasian, Sarah K., Oo, Htoo Zarni, Negri, Gian Luca, Lin, Yongshun, Zou, Jizhong, Mallon, Barbara S., Maude, Shannon, Teachey, David T., Barrett, David M., Orentas, Rimas J., Daugaard, Mads, Sorensen, Poul H. B., Grupp, Stephan A., Fry, Terry J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2015
Gaiak:
Lymphoid Neoplasia
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520878/
https://ncbi.nlm.nih.gov/pubmed/26041741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-612903
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