Eradication of B-ALL using chimeric antigen receptor–expressing T cells targeting the TSLPR oncoprotein

Adoptive transfer of T cells genetically modified to express chimeric antigen receptors (CARs) targeting the CD19 B cell–associated protein have demonstrated potent activity against relapsed/refractory B-lineage acute lymphoblastic leukemia (B-ALL). Not all patients respond, and CD19-negative relaps...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood
Main Authors: Qin, Haiying, Cho, Monica, Haso, Waleed, Zhang, Ling, Tasian, Sarah K., Oo, Htoo Zarni, Negri, Gian Luca, Lin, Yongshun, Zou, Jizhong, Mallon, Barbara S., Maude, Shannon, Teachey, David T., Barrett, David M., Orentas, Rimas J., Daugaard, Mads, Sorensen, Poul H. B., Grupp, Stephan A., Fry, Terry J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520878/
https://ncbi.nlm.nih.gov/pubmed/26041741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-612903
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados