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Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination
We have recently identified lens epithelium-derived growth factor (LEDGF/p75, also known as PSIP1) as a component of the homologous recombination DNA repair machinery. Through its Pro-Trp-Trp-Pro (PWWP) domain, LEDGF/p75 binds to histone marks associated with active transcription and promotes DNA en...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4797281/ https://ncbi.nlm.nih.gov/pubmed/26721387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1526 |
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