Increased CSF Aβ during the very early phase of cerebral Aβ deposition in mouse models

Abnormalities in brains of Alzheimer's disease (AD) patients are thought to start long before the first clinical symptoms emerge. The identification of affected individuals at this ‘preclinical AD’ stage relies on biomarkers such as decreased levels of the amyloid-β peptide (Aβ) in the cerebros...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Maia, Luis F, Kaeser, Stephan A, Reichwald, Julia, Lambert, Marius, Obermüller, Ulrike, Schelle, Juliane, Odenthal, Jörg, Martus, Peter, Staufenbiel, Matthias, Jucker, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520655/
https://ncbi.nlm.nih.gov/pubmed/25978969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505026
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