Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA

Antibacterial drugs with novel scaffolds and new mechanisms of action are desperately needed to address the growing problem of antibiotic resistance. The periplasmic oxidative folding system in Gram-negative bacteria represents a possible target for anti-virulence antibacterials. By targeting virule...

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Vydáno v:PLoS One
Hlavní autoři: Duprez, Wilko, Bachu, Prabhakar, Stoermer, Martin J., Tay, Stephanie, McMahon, Róisín M., Fairlie, David P., Martin, Jennifer L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520593/
https://ncbi.nlm.nih.gov/pubmed/26225423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133805
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