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Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA

Antibacterial drugs with novel scaffolds and new mechanisms of action are desperately needed to address the growing problem of antibiotic resistance. The periplasmic oxidative folding system in Gram-negative bacteria represents a possible target for anti-virulence antibacterials. By targeting virule...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Duprez, Wilko, Bachu, Prabhakar, Stoermer, Martin J., Tay, Stephanie, McMahon, Róisín M., Fairlie, David P., Martin, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520593/
https://ncbi.nlm.nih.gov/pubmed/26225423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133805
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