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Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases

The bacterial disulfide machinery is an attractive molecular target for developing new antibacterials because it is required for the production of multiple virulence factors. The archetypal disulfide oxidase proteins in Escherichia coli (Ec) are DsbA and DsbB, which together form a functional unit:...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Premkumar, Lakshmanane, Heras, Begoña, Duprez, Wilko, Walden, Patricia, Halili, Maria, Kurth, Fabian, Fairlie, David P., Martin, Jennifer L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792642/
https://ncbi.nlm.nih.gov/pubmed/24100317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444913017800
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