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Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases

The bacterial disulfide machinery is an attractive molecular target for developing new antibacterials because it is required for the production of multiple virulence factors. The archetypal disulfide oxidase proteins in Escherichia coli (Ec) are DsbA and DsbB, which together form a functional unit:...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Premkumar, Lakshmanane, Heras, Begoña, Duprez, Wilko, Walden, Patricia, Halili, Maria, Kurth, Fabian, Fairlie, David P., Martin, Jennifer L.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: International Union of Crystallography 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792642/
https://ncbi.nlm.nih.gov/pubmed/24100317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444913017800
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