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Activity of the HMGB1-Derived Immunostimulatory Peptide Hp91 Resides in the Helical C-terminal Portion and is Enhanced by Dimerization
We have previously shown that an 18 amino acid long peptide, named Hp91, whose sequence corresponds to a region within the endogenous protein HMGB1, activates dendritic cells (DCs) and acts as adjuvant in vivo by potentiating Th1-type antigen-specific immune responses. We analyzed the structure-func...
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| Publicado no: | Mol Immunol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4520421/ https://ncbi.nlm.nih.gov/pubmed/24172222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2013.09.007 |
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