TLR4-dependent activation of dendritic cells by an HMGB1-derived peptide adjuvant

High mobility group box protein 1 (HMGB1) acts as an endogenous danger molecule that is released from necrotic cells and activated macrophages. We have previously shown that peptide Hp91, whose sequence corresponds to an area within the B-Box domain of HMGB1, activates dendritic cells (DCs) and acts...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Saenz, Rebecca, Futalan, Diahnn, Leutenez, Lien, Eekhout, Fien, Fecteau, Jessie F, Sundelius, Simeon, Sundqvist, Stig, Larsson, Marie, Hayashi, Tomoko, Minev, Boris, Carson, Dennis, Esener, Sadik, Messmer, Bradley, Messmer, Davorka
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261565/
https://ncbi.nlm.nih.gov/pubmed/25123824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-211
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