Enhanced anti-tumor immune responses and delay of tumor development in human epidermal growth factor receptor 2 mice immunized with an immunostimulatory peptide in poly(D,L-lactic-co-glycolic) acid nanoparticles

INTRODUCTION: Cancer vaccines have the potential to induce curative anti-tumor immune responses and better adjuvants may improve vaccine efficacy. We have previously shown that Hp91, a peptide derived from the B box domain in high-mobility group box protein 1 (HMGB1), acts as a potent immune adjuvan...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Campbell, Diahnn F, Saenz, Rebecca, Bharati, Ila S, Seible, Daniel, Zhang, Liangfang, Esener, Sadik, Messmer, Bradley, Larsson, Marie, Messmer, Davorka
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407876/
https://ncbi.nlm.nih.gov/pubmed/25882711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0552-9
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