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De-DUFing the DUFs: Deciphering distant evolutionary relationships of Domains of Unknown Function using sensitive homology detection methods

BACKGROUND: In the post-genomic era where sequences are being determined at a rapid rate, we are highly reliant on computational methods for their tentative biochemical characterization. The Pfam database currently contains 3,786 families corresponding to “Domains of Unknown Function” (DUF) or “Unch...

詳細記述

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書誌詳細
出版年:Biol Direct
主要な著者: Mudgal, Richa, Sandhya, Sankaran, Chandra, Nagasuma, Srinivasan, Narayanaswamy
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520260/
https://ncbi.nlm.nih.gov/pubmed/26228684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-015-0069-2
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