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De-DUFing the DUFs: Deciphering distant evolutionary relationships of Domains of Unknown Function using sensitive homology detection methods
BACKGROUND: In the post-genomic era where sequences are being determined at a rapid rate, we are highly reliant on computational methods for their tentative biochemical characterization. The Pfam database currently contains 3,786 families corresponding to “Domains of Unknown Function” (DUF) or “Unch...
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| Pubblicato in: | Biol Direct |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4520260/ https://ncbi.nlm.nih.gov/pubmed/26228684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-015-0069-2 |
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