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Sinulariolide Suppresses Human Hepatocellular Carcinoma Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 through MAPKs and PI3K/Akt Signaling Pathways

Sinulariolide is an active compound isolated from the cultured soft coral Sinularia flexibilis. In this study, we investigate the migration and invasion effects of sinulariolide in hepatocellular carcinoma cell HA22T. Sinulariolide inhibited the migration and invasion effects of hepatocellular carci...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Wu, Yu-Jen, Neoh, Choo-Aun, Tsao, Chia-Yu, Su, Jui-Hsin, Li, Hsing-Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519960/
https://ncbi.nlm.nih.gov/pubmed/26204832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160716469
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