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Sinulariolide Suppresses Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase through the PI3K/AKT/mTOR Signaling Pathway in Human Bladder Cancer Cells

Sinulariolide is a natural product extracted from the cultured-type soft coral Sinularia flexibilis, and possesses bioactivity against the movement of several types of cancer cells. However, the molecular pathway behind its effects on human bladder cancer remain poorly understood. Using a human blad...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Cheng, Te-Chih, Din, Zhong-Hao, Su, Jui-Hsin, Wu, Yu-Jen, Liu, Chih-I
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577593/
https://ncbi.nlm.nih.gov/pubmed/28767067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md15080238
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