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Flaccidoxide-13-Acetate Extracted from the Soft Coral Cladiella kashmani Reduces Human Bladder Cancer Cell Migration and Invasion through Reducing Activation of the FAK/PI3K/AKT/mTOR Signaling Pathway

Metastasis of cancer is the cause of the majority of cancer deaths. Active compound flaccidoxide-13-acetate, isolated from the soft coral Cladiella kashmani, has been found to exhibit anti-tumor activity. In this study, Boyden chamber analysis, Western blotting and gelatin zymography assays indicate...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Neoh, Choo-Aun, Wu, Wen-Tung, Dai, Guo-Fong, Su, Jui-Hsin, Liu, Chih-I, Su, Tzu-Rong, Wu, Yu-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017900/
https://ncbi.nlm.nih.gov/pubmed/29280977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23010058
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