Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Downregulates ELOVL1 Gene Expression and Fatty Acid Synthesis in Goat Fetal Fibroblasts

Elongation of very-long-chain fatty acids 1 (ELOVL1) is a ubiquitously expressed gene that belongs to the ELOVL family and regulates the synthesis of very-long-chain fatty acids (VLCFAs) and sphingolipids, from yeast to mammals. Mammalian target of rapamycin complex 1 (mTORC1) is a central regulator...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wang, Weipeng, He, Qiburi, Guo, Zhixin, Yang, Limin, Bao, Lili, Bao, Wenlei, Zheng, Xu, Wang, Yanfeng, Wang, Zhigang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519958/
https://ncbi.nlm.nih.gov/pubmed/26204830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160716440
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