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Mevalonate Pathway Blockade, Mitochondrial Dysfunction and Autophagy: A Possible Link
The mevalonate pathway, crucial for cholesterol synthesis, plays a key role in multiple cellular processes. Deregulation of this pathway is also correlated with diminished protein prenylation, an important post-translational modification necessary to localize certain proteins, such as small GTPases,...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4519939/ https://ncbi.nlm.nih.gov/pubmed/26184189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160716067 |
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