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Mevalonate Pathway Blockade, Mitochondrial Dysfunction and Autophagy: A Possible Link

The mevalonate pathway, crucial for cholesterol synthesis, plays a key role in multiple cellular processes. Deregulation of this pathway is also correlated with diminished protein prenylation, an important post-translational modification necessary to localize certain proteins, such as small GTPases,...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Tricarico, Paola Maura, Crovella, Sergio, Celsi, Fulvio
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519939/
https://ncbi.nlm.nih.gov/pubmed/26184189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160716067
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