Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria

Recent studies on the respiratory chain of Ascaris suum showed that the mitochondrial NADH-fumarate reductase system composed of complex I, rhodoquinone and complex II plays an important role in the anaerobic energy metabolism of adult A. suum. The system is the major pathway of energy metabolism fo...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Inaoka, Daniel Ken, Shiba, Tomoo, Sato, Dan, Balogun, Emmanuel Oluwadare, Sasaki, Tsuyoshi, Nagahama, Madoka, Oda, Masatsugu, Matsuoka, Shigeru, Ohmori, Junko, Honma, Teruki, Inoue, Masayuki, Kita, Kiyoshi, Harada, Shigeharu
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519900/
https://ncbi.nlm.nih.gov/pubmed/26198225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160715287
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