Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria

Recent studies on the respiratory chain of Ascaris suum showed that the mitochondrial NADH-fumarate reductase system composed of complex I, rhodoquinone and complex II plays an important role in the anaerobic energy metabolism of adult A. suum. The system is the major pathway of energy metabolism fo...

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Publicado en:Int J Mol Sci
Main Authors: Inaoka, Daniel Ken, Shiba, Tomoo, Sato, Dan, Balogun, Emmanuel Oluwadare, Sasaki, Tsuyoshi, Nagahama, Madoka, Oda, Masatsugu, Matsuoka, Shigeru, Ohmori, Junko, Honma, Teruki, Inoue, Masayuki, Kita, Kiyoshi, Harada, Shigeharu
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519900/
https://ncbi.nlm.nih.gov/pubmed/26198225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160715287
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