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Some (dis)assembly required: partial unfolding in the Par-6 allosteric switch
Allostery is commonly described as a functional connection between two distant sites in a protein, where a binding event at one site alters affinity at the other. Here, we review the conformational dynamics that encode an allosteric switch in the PDZ domain of Par-6, which is a scaffold protein that...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Biophys Rev |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Springer Berlin Heidelberg
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4519835/ https://ncbi.nlm.nih.gov/pubmed/26236405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-015-0164-8 |
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