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Meta-Analysis and Potential Role of Preexisting Heterosubtypic Cellular Immunity Based on Variations in Disease Severity Outcomes for Influenza Live Viral Challenges in Humans

Influenza live viral challenges in humans are valuable models for testing the efficacy of vaccines and antiviral agents. Volunteers are treated with an investigational agent, and their clinical outcomes postchallenge are compared to those of placebo-treated volunteers. Despite using a common protoco...

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Bibliografiske detaljer
Udgivet i:Clin Vaccine Immunol
Main Authors: Pleguezuelos, Olga, Robinson, Stuart, Fernandez, Ana, Stoloff, Gregory A., Caparrós-Wanderley, Wilson
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519729/
https://ncbi.nlm.nih.gov/pubmed/26084515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00101-15
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