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Meta-Analysis and Potential Role of Preexisting Heterosubtypic Cellular Immunity Based on Variations in Disease Severity Outcomes for Influenza Live Viral Challenges in Humans

Influenza live viral challenges in humans are valuable models for testing the efficacy of vaccines and antiviral agents. Volunteers are treated with an investigational agent, and their clinical outcomes postchallenge are compared to those of placebo-treated volunteers. Despite using a common protoco...

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Detalhes bibliográficos
Publicado no:Clin Vaccine Immunol
Main Authors: Pleguezuelos, Olga, Robinson, Stuart, Fernandez, Ana, Stoloff, Gregory A., Caparrós-Wanderley, Wilson
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519729/
https://ncbi.nlm.nih.gov/pubmed/26084515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00101-15
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