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Synthetic immunotherapy induces HIV virus specific Th1 cytotoxic response and death of an HIV-1 infected human cell line through classic complement activation

BACKGROUND: This manuscript describes the development of a novel synthetic immunotherapy (HIV-v) composed of four multi-epitope polypeptides targeting conserved regions in the Nef, Rev, Vif and Vpr viral proteins. Immunogenicity and cytotoxicity of HIV-v are discussed. METHODS: Short conserved T-cel...

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書誌詳細
主要な著者: Pleguezuelos, Olga, Stoloff, Gregory A, Caparrós-Wanderley, Wilson
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626621/
https://ncbi.nlm.nih.gov/pubmed/23557359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-107
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