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IL-4 is required for sex differences in vulnerability to focal ischemia in mice

BACKGROUND AND PURPOSE: IL-4 protects from middle cerebral artery occlusion (MCAO) in male mice. Females generally show less injury in response to the same ischemic challenge, but the underlying mechanisms are not fully understood. We tested the importance of IL-4 in female protection using IL-4 kno...

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Dades bibliogràfiques
Publicat a:Stroke
Autors principals: Xiong, Xiaoxing, Xu, Lijun, Wei, Liang, White, Robin E, Ouyang, Yi-Bing, Giffard, Rona G.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519392/
https://ncbi.nlm.nih.gov/pubmed/26130091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.008897
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