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IL-4 is required for sex differences in vulnerability to focal ischemia in mice

BACKGROUND AND PURPOSE: IL-4 protects from middle cerebral artery occlusion (MCAO) in male mice. Females generally show less injury in response to the same ischemic challenge, but the underlying mechanisms are not fully understood. We tested the importance of IL-4 in female protection using IL-4 kno...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Xiong, Xiaoxing, Xu, Lijun, Wei, Liang, White, Robin E, Ouyang, Yi-Bing, Giffard, Rona G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519392/
https://ncbi.nlm.nih.gov/pubmed/26130091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.008897
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