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Increased brain injury and worsened neurological outcome in IL-4 Knockout Mice Following Transient Focal Cerebral Ischemia

BACKGROUND AND PURPOSE: Stroke causes brain injury with activation of an inflammatory response which can contribute to injury. We tested the hypothesis that the anti-inflammatory cytokine IL-4 reduces injury following stroke using IL-4 knockout (KO) adult male mice. METHODS: IL-4 KO and wild type (W...

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Main Authors: Xiong, Xiaoxing, Barreto, George, Xu, Lijun, Ouyang, YiBing, Xie, Xinmin, Giffard, Rona G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128567/
https://ncbi.nlm.nih.gov/pubmed/21597016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.593772
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