CNS myelin wrapping is driven by actin disassembly

Myelin is essential in vertebrates for the rapid propagation of action potentials, but the molecular mechanisms driving its formation remain largely unknown. Here we show that the initial stage of process extension and axon ensheathment by oligodendrocytes requires dynamic actin filament assembly by...

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Bibliographic Details
Published in:Dev Cell
Main Authors: Zuchero, J. Bradley, Fu, Meng-meng, Sloan, Steven A., Ibrahim, Adiljan, Olson, Andrew, Zaremba, Anita, Dugas, Jason C., Wienbar, Sophia, Caprariello, Andrew V., Kantor, Christopher, Leonoudakis, Dmitri, Lariosa-Willingham, Karen, Kronenberg, Golo, Gertz, Karen, Soderling, Scott H., Miller, Robert H., Barres, Ben A.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519368/
https://ncbi.nlm.nih.gov/pubmed/26166300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.06.011
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