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The T3-induced gene KLF9 regulates oligodendrocyte differentiation and myelin regeneration

Hypothyroidism is a well-described cause of hypomyelination. In addition, thyroid hormone (T3) has recently been shown to enhance remyelination in various animal models of CNS demyelination. What are the ways in which T3 promotes the development and regeneration of healthy myelin? To begin to unders...

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Publicat a:Mol Cell Neurosci
Autors principals: Dugas, Jason C., Ibrahim, Adiljan, Barres, Ben A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441621/
https://ncbi.nlm.nih.gov/pubmed/22472204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2012.03.007
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