IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4(+) T Cells and IFN-γ

African trypanosomes are extracellular protozoan parasites causing a chronic debilitating disease associated with a persistent inflammatory response. Maintaining the balance of the inflammatory response via downregulation of activation of M1-type myeloid cells was previously shown to be crucial to a...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Liu, Gongguan, Xu, Jinjun, Wu, Hui, Sun, Donglei, Zhang, Xiquan, Zhu, Xiaoping, Magez, Stefan, Shi, Meiqing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519326/
https://ncbi.nlm.nih.gov/pubmed/26222157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005065
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