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Distinct Contributions of CD4(+) and CD8(+) T Cells to Pathogenesis of Trypanosoma brucei Infection in the Context of Gamma Interferon and Interleukin-10

Although gamma interferon (IFN-γ) and interleukin-10 (IL-10) have been shown to be critically involved in the pathogenesis of African trypanosomiasis, the contributions to this disease of CD4(+) and CD8(+) T cells, the major potential producers of the two cytokines, are incompletely understood. Here...

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Опубликовано в: :Infect Immun
Главные авторы: Liu, Gongguan, Sun, Donglei, Wu, Hui, Zhang, Mingshun, Huan, Haixia, Xu, Jinjun, Zhang, Xiquan, Zhou, Hong, Shi, Meiqing
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468542/
https://ncbi.nlm.nih.gov/pubmed/25916989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00357-15
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