A Novel Antiviral Target Structure Involved in the RNA Binding, Dimerization, and Nuclear Export Functions of the Influenza A Virus Nucleoprotein

Developing antiviral therapies for influenza A virus (IAV) infection is an ongoing process because of the rapid rate of antigenic mutation and the emergence of drug-resistant viruses. The ideal strategy is to develop drugs that target well-conserved, functionally restricted, and unique surface struc...

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Publicat a:PLoS Pathog
Autors principals: Kakisaka, Michinori, Sasaki, Yutaka, Yamada, Kazunori, Kondoh, Yasumitsu, Hikono, Hirokazu, Osada, Hiroyuki, Tomii, Kentaro, Saito, Takehiko, Aida, Yoko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519322/
https://ncbi.nlm.nih.gov/pubmed/26222066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005062
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