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Revisiting amino acid substitution matrices for identifying distantly related proteins

Motivation: Although many amino acid substitution matrices have been developed, it has not been well understood which is the best for similarity searches, especially for remote homology detection. Therefore, we collected information related to existing matrices, condensed it and derived a novel matr...

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Detalles Bibliográficos
Main Authors: Yamada, Kazunori, Tomii, Kentaro
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904525/
https://ncbi.nlm.nih.gov/pubmed/24281694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt694
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