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Revisiting amino acid substitution matrices for identifying distantly related proteins

Motivation: Although many amino acid substitution matrices have been developed, it has not been well understood which is the best for similarity searches, especially for remote homology detection. Therefore, we collected information related to existing matrices, condensed it and derived a novel matr...

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Bibliografiske detaljer
Main Authors: Yamada, Kazunori, Tomii, Kentaro
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904525/
https://ncbi.nlm.nih.gov/pubmed/24281694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt694
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