Non-Hematopoietic and Hematopoietic SIRPα Signaling Differently Regulates Murine B Cell Maturation in Bone Marrow and Spleen

B lymphocyte development occurs in the bone marrow, while final differentiation and maturation can occur in both the bone marrow and the spleen. Here we provide evidence that signal regulatory protein α (SIRPα), an Ig-superfamily ITIM-receptor expressed by myeloid but not by lymphoid cells, is invol...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kolan, Shrikant Shantilal, Lejon, Kristina, Koskinen Holm, Cecilia, Sulniute, Rima, Lundberg, Pernilla, Matozaki, Takashi, Oldenborg, Per-Arne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519279/
https://ncbi.nlm.nih.gov/pubmed/26222253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134113
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