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Inflammasomes: Mechanism of Action, Role in Disease, and Therapeutics

The inflammasomes are innate immune system receptors/sensors that regulate the activation of caspase-1 and induce inflammation in response to infectious microbes and molecules derived from host proteins. It has been implicated in a host of inflammatory disorders. Recent developments have greatly enh...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Guo, Haitao, Callaway, Justin B., Ting, Jenny P.-Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519035/
https://ncbi.nlm.nih.gov/pubmed/26121197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3893
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