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Equalizer reduces SNP bias in Affymetrix microarrays

BACKGROUND: Gene expression microarrays measure the levels of messenger ribonucleic acid (mRNA) in a sample using probe sequences that hybridize with transcribed regions. These probe sequences are designed using a reference genome for the relevant species. However, most model organisms and all human...

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Publié dans:BMC Bioinformatics
Auteur principal: Quigley, David
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518889/
https://ncbi.nlm.nih.gov/pubmed/26223252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0669-y
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