Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47.

The immediate early protein ICP47 of herpes simplex virus (HSV) inhibits the transporter for antigen processing (TAP)-mediated translocation of antigen-derived peptides across the endoplasmic reticulum (ER) membrane. This interference prevents assembly of peptides with class I MHC molecules in the E...

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Pubblicato in:	EMBO J
Autori principali:	Ahn, K, Meyer, T H, Uebel, S, Sempé, P, Djaballah, H, Yang, Y, Peterson, P A, Früh, K, Tampé, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC451885/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8670825/
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