Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47.

The immediate early protein ICP47 of herpes simplex virus (HSV) inhibits the transporter for antigen processing (TAP)-mediated translocation of antigen-derived peptides across the endoplasmic reticulum (ER) membrane. This interference prevents assembly of peptides with class I MHC molecules in the E...

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Dettagli Bibliografici
Autori principali: Ahn, K, Meyer, T H, Uebel, S, Sempé, P, Djaballah, H, Yang, Y, Peterson, P A, Früh, K, Tampé, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC451885/
https://ncbi.nlm.nih.gov/pubmed/8670825
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