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Recombinant IgG2a Fc (M045(1)) Multimers Effectively Suppress Experimental Autoimmune Myasthenia Gravis
Myasthenia gravis (MG) is an autoimmune disorder caused by target-specific pathogenic antibodies directed toward postsynaptic neuromuscular junction (NMJ) proteins, most commonly the skeletal muscle nicotinic acetylcholine receptor (AChR). In MG, high-affinity anti-AChR Abs binding to the NMJ lead t...
Guardat en:
| Publicat a: | J Autoimmun |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4518541/ https://ncbi.nlm.nih.gov/pubmed/24388113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.12.014 |
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