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Inhibition of CDK4/6 as a novel therapeutic option for neuroblastoma

BACKGROUND: Neuroblastoma is a neural crest-derived tumor and is the most common cancer in children less than 1 year of age. We hypothesized that aberrations in genes that control the cell cycle could play an important role in the pathogenesis of neuroblastoma and could provide a tractable therapeut...

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Publicat a:Cancer Cell Int
Autors principals: Rihani, Ali, Vandesompele, Jo, Speleman, Frank, Van Maerken, Tom
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518532/
https://ncbi.nlm.nih.gov/pubmed/26225123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-015-0224-y
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