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An integrated multi-study analysis of intra-subject variability in cerebrospinal fluid amyloid-β concentrations collected by lumbar puncture and indwelling lumbar catheter

INTRODUCTION: Amyloid-β (Aβ) has been investigated as a diagnostic biomarker and therapeutic drug target. Recent studies found that cerebrospinal fluid (CSF) Aβ fluctuates over time, including as a diurnal pattern, and increases in absolute concentration with serial collection. It is currently unkno...

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Bibliografiska uppgifter
I publikationen:Alzheimers Res Ther
Huvudupphovsmän: Lucey, Brendan P., Gonzales, Celedon, Das, Ujjwas, Li, Jinhe, Siemers, Eric R., Slemmon, J. Randall, Bateman, Randall J., Huang, Yafei, Fox, Gerard B., Claassen, Jurgen A.H.R., Slats, Diane, Verbeek, Marcel M., Tong, Gary, Soares, Holly, Savage, Mary J., Kennedy, Matthew, Forman, Mark, Sjögren, Magnus, Margolin, Richard, Chen, Xia, Farlow, Martin R., Dean, Robert A., Waring, Jeffrey F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518529/
https://ncbi.nlm.nih.gov/pubmed/26225140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-015-0136-z
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