Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels

Alpha-1 antitrypsin (AAT) encoded by SERPINA1 is an acute-phase inflammation marker, and AAT deficiency (AATD) is known as one of the common genetic disorders in European populations. However, no genetic determinants to AAT levels apart from the SERPINA gene clusters have been identified to date. He...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Setoh, Kazuya, Terao, Chikashi, Muro, Shigeo, Kawaguchi, Takahisa, Tabara, Yasuharu, Takahashi, Meiko, Nakayama, Takeo, Kosugi, Shinji, Sekine, Akihiro, Yamada, Ryo, Mishima, Michiaki, Matsuda, Fumihiko
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518310/
https://ncbi.nlm.nih.gov/pubmed/26174136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8754
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items