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Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels
Alpha-1 antitrypsin (AAT) encoded by SERPINA1 is an acute-phase inflammation marker, and AAT deficiency (AATD) is known as one of the common genetic disorders in European populations. However, no genetic determinants to AAT levels apart from the SERPINA gene clusters have been identified to date. He...
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| 發表在: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Pub. Group
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4518310/ https://ncbi.nlm.nih.gov/pubmed/26174136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8754 |
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