Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels

Alpha-1 antitrypsin (AAT) encoded by SERPINA1 is an acute-phase inflammation marker, and AAT deficiency (AATD) is known as one of the common genetic disorders in European populations. However, no genetic determinants to AAT levels apart from the SERPINA gene clusters have been identified to date. He...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Setoh, Kazuya, Terao, Chikashi, Muro, Shigeo, Kawaguchi, Takahisa, Tabara, Yasuharu, Takahashi, Meiko, Nakayama, Takeo, Kosugi, Shinji, Sekine, Akihiro, Yamada, Ryo, Mishima, Michiaki, Matsuda, Fumihiko
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Pub. Group 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518310/
https://ncbi.nlm.nih.gov/pubmed/26174136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8754
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