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Direct Coupling of a Seven-Transmembrane-Span Receptor to a Gαi G-Protein Regulatory Motif Complex

Group II activator of G-protein signaling (AGS) proteins contain one or more G-protein regulatory motifs (GPR), which serve as docking sites for Gαi(GDP) independent of Gβγ and stabilize the GDP-bound conformation of Gαi, acting as guanine nucleotide dissociation inhibitors. The GαGPR interaction is...

詳細記述

保存先:
書誌詳細
出版年:Mol Pharmacol
主要な著者: Robichaux, William G., Oner, Sukru S., Lanier, Stephen M., Blumer, Joe B.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Pharmacology and Experimental Therapeutics 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518091/
https://ncbi.nlm.nih.gov/pubmed/25972449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.097741
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