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Differentiation-Associated Downregulation of Poly(ADP-Ribose) Polymerase-1 Expression in Myoblasts Serves to Increase Their Resistance to Oxidative Stress

Poly(ADP-ribose) polymerase 1 (PARP-1), the major isoform of the poly (ADP-ribose) polymerase family, is a constitutive nuclear and mitochondrial protein with well-recognized roles in various essential cellular functions such as DNA repair, signal transduction, apoptosis, as well as in a variety of...

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Vydáno v:PLoS One
Hlavní autoři: Oláh, Gábor, Szczesny, Bartosz, Brunyánszki, Attila, López-García, Isabel A., Gerö, Domokos, Radák, Zsolt, Szabo, Csaba
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517814/
https://ncbi.nlm.nih.gov/pubmed/26218895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134227
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