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Partially Evoked Epithelial-Mesenchymal Transition (EMT) Is Associated with Increased TGFβ Signaling within Lesional Scleroderma Skin

The origin of myofibroblasts in fibrotic conditions remains unknown and in systemic sclerosis (SSc) it has been proposed that activation of local fibroblasts, trans-differentiation of perivascular or vascular cells, recruitment of fibrocyte progenitors, or epithelial to mesenchymal transition (EMT)...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nikitorowicz-Buniak, Joanna, Denton, Christopher P., Abraham, David, Stratton, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517793/
https://ncbi.nlm.nih.gov/pubmed/26217927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134092
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