Oral Administration of P. gingivalis Induces Dysbiosis of Gut Microbiota and Impaired Barrier Function Leading to Dissemination of Enterobacteria to the Liver

Although periodontitis has been implicated as a risk factor for various systemic diseases, the precise mechanisms by which periodontitis induces systemic disease remain to be elucidated. We have previously revealed that repeated oral administration of Porphyromonas gingivalis elicits endotoxemia via...

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Udgivet i:PLoS One
Main Authors: Nakajima, Mayuka, Arimatsu, Kei, Kato, Tamotsu, Matsuda, Yumi, Minagawa, Takayoshi, Takahashi, Naoki, Ohno, Hiroshi, Yamazaki, Kazuhisa
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517782/
https://ncbi.nlm.nih.gov/pubmed/26218067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134234
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