ROS Accumulation by PEITC Selectively Kills Ovarian Cancer Cells via UPR-Mediated Apoptosis

Unfolded protein response (UPR) is crucial for both survival and death of mammalian cells, which is regulated by reactive oxygen species (ROS) and nutrient depletion. In this study, we demonstrated the effect of ROS-accumulation, induced by β-phenethyl isothiocyanate (PEITC), on UPR-mediated apoptos...

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Bibliografiska uppgifter
I publikationen:Front Oncol
Huvudupphovsmän: Hong, Yoon-Hee, Uddin, Md. Hafiz, Jo, Untek, Kim, Boyun, Song, Jiyoung, Suh, Dong Hoon, Kim, Hee Seung, Song, Yong Sang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2015
Ämnen:
Oncology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517521/
https://ncbi.nlm.nih.gov/pubmed/26284193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00167
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