ROS Accumulation by PEITC Selectively Kills Ovarian Cancer Cells via UPR-Mediated Apoptosis

Unfolded protein response (UPR) is crucial for both survival and death of mammalian cells, which is regulated by reactive oxygen species (ROS) and nutrient depletion. In this study, we demonstrated the effect of ROS-accumulation, induced by β-phenethyl isothiocyanate (PEITC), on UPR-mediated apoptos...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Hong, Yoon-Hee, Uddin, Md. Hafiz, Jo, Untek, Kim, Boyun, Song, Jiyoung, Suh, Dong Hoon, Kim, Hee Seung, Song, Yong Sang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517521/
https://ncbi.nlm.nih.gov/pubmed/26284193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00167
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