One-step biosynthesis of α-ketoisocaproate from l-leucine by an Escherichia coli whole-cell biocatalyst expressing an l-amino acid deaminase from Proteus vulgaris

This work aimed to develop a whole-cell biotransformation process for the production of α-ketoisocaproate from L-leucine. A recombinant Escherichia coli strain was constructed by expressing an L-amino acid deaminase from Proteus vulgaris. To enhance α-ketoisocaproate production, the reaction conditi...

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Vydáno v:Sci Rep
Hlavní autoři: Song, Yang, Li, Jianghua, Shin, Hyun-dong, Du, Guocheng, Liu, Long, Chen, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517468/
https://ncbi.nlm.nih.gov/pubmed/26217895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12614
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