IL6 secreted by Ewing sarcoma tumor microenvironment confers anti-apoptotic and cell-disseminating paracrine responses in Ewing sarcoma cells

BACKGROUND: The prognosis of patients with Ewing sarcoma (ES) has improved over the course of the last decades. However, those patients suffering from metastatic and recurrent ES still have only poor chances of survival and require new therapeutic approaches. Interleukin-6 (IL6) is a pleiotropic cyt...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Lissat, Andrej, Joerschke, Mandy, Shinde, Dheeraj A., Braunschweig, Till, Meier, Angelina, Makowska, Anna, Bortnick, Rachel, Henneke, Philipp, Herget, Georg, Gorr, Thomas A., Kontny, Udo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517368/
https://ncbi.nlm.nih.gov/pubmed/26215971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1564-7
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