IL6 secreted by Ewing sarcoma tumor microenvironment confers anti-apoptotic and cell-disseminating paracrine responses in Ewing sarcoma cells

BACKGROUND: The prognosis of patients with Ewing sarcoma (ES) has improved over the course of the last decades. However, those patients suffering from metastatic and recurrent ES still have only poor chances of survival and require new therapeutic approaches. Interleukin-6 (IL6) is a pleiotropic cyt...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Lissat, Andrej, Joerschke, Mandy, Shinde, Dheeraj A., Braunschweig, Till, Meier, Angelina, Makowska, Anna, Bortnick, Rachel, Henneke, Philipp, Herget, Georg, Gorr, Thomas A., Kontny, Udo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517368/
https://ncbi.nlm.nih.gov/pubmed/26215971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1564-7
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