IL6 secreted by Ewing sarcoma tumor microenvironment confers anti-apoptotic and cell-disseminating paracrine responses in Ewing sarcoma cells

BACKGROUND: The prognosis of patients with Ewing sarcoma (ES) has improved over the course of the last decades. However, those patients suffering from metastatic and recurrent ES still have only poor chances of survival and require new therapeutic approaches. Interleukin-6 (IL6) is a pleiotropic cyt...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Lissat, Andrej, Joerschke, Mandy, Shinde, Dheeraj A., Braunschweig, Till, Meier, Angelina, Makowska, Anna, Bortnick, Rachel, Henneke, Philipp, Herget, Georg, Gorr, Thomas A., Kontny, Udo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517368/
https://ncbi.nlm.nih.gov/pubmed/26215971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1564-7
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