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Interferon β and Anti-PD-1/PD-L1 Checkpoint Blockade Cooperate in NK Cell-Mediated Killing of Nasopharyngeal Carcinoma Cells

Nasopharyngeal carcinoma (NPC) is a highly malignant epithelial cancer linked to EBV infection. Addition of interferon-β (IFNβ) to chemo- and radiochemotherapy has led to survival rates >90% in children and adolescents. As NPC cells are sensitive to apoptosis via tumor necrosis factor-related apo...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Makowska, Anna, Braunschweig, Till, Denecke, Bernd, Shen, Lian, Baloche, Valentin, Busson, Pierre, Kontny, Udo
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617170/
https://ncbi.nlm.nih.gov/pubmed/31295651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.04.017
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